Contact Information
Department of Neurobiology and Behavior
University of California, Irvine
Irvine, CA 92697-4550
Tel: 949.824.7833
Email:ismith@uci.edu
Current Research Interests
| Employment: |
|
|
|
| University of California , Irvine , Dept. of Neurobiology and Behavior |
|
| 2006-present |
Project Scientist |
|
| 2003-2006 |
Post Doctoral Research Fellow |
|
|
|
| Education and Training: |
|
|
|
| University of Leeds , UK , The School of Medicine, Institute for Cardiovascular Research |
|
| 1999-2003 |
Ph.D |
|
|
|
| University of Leeds , UK , Department of Pharmacology. |
|
| 1996-1999 |
B.Sc. Hons. Pharmacology 2.1 |
|
|
|
2006-present University of California , Irvine (Department of Neurobiology and Behavior – Ian Parker, PI) Mechanisms of intracellular neuronal calcium signaling underlying normal and neurodegenerative processes. The physiology of elementary calcium release events in neurons particularly in familial hemiplegic migraine and Parkinson’s disease using multi-photon, confocal and total internal reflection microscopy.
2003-2006 University of California, Irvine (Department of Neurobiology and Behavior - Frank LaFerla, PI) In vitro fluorescent imaging and molecular biological studies examining mechanisms of neuronal calcium signaling, and mutations related to Alzheimer's disease and neurodegenerative diseases.
1999-2003 University of Leeds, United Kingdom (Institute for Cardiovascular Research – Chris Peers, PI) Hypoxia and amyloid β peptide modulation of calcium signaling in the human neuroblastoma SH-SY5Y and rat type I cortical astrocytes. Examining the molecular link between stroke and Alzheimer’s disease.
1996-1999 University of Leeds, United Kingdom (Department of Pharmacology – Final year dissertation project in collaboration with Pfizer Global Research) An in vitro study to characterise the binding of [ 3H]-dofetilide to various tissue preparations and cell lines.
|
