Ian Parker's CV

Feb. 2, 2005



Department of Neurobiology and Behavior,
University of California , Irvine , CA 92697-4550
office: (949) 824 7332
fax: (949) 824 2447
email: iparker@uci.edu

Degrees - B.Sc. (Physiology, University of London . 1972)
  Ph.D. (Physiology, University of London . 1984)

Academic and Research Positions
1975 - 1984 Research Assistant, Department of Biophysics, University College London , UK .
1984 - 1990 Assistant Professor, Department of Psychobiology, University of California , Irvine , U.S.A.
1990 - 1995 Associate Professor, Department of Psychobiology, University of California , Irvine , U.S.A.
1995 - 1996 Visiting Professor, Department of Physiology, University of Maryland School of Medicine , Baltimore , U.S.A.  
1996 - 1997 Acting Chair, Department of Psychobiology, University of California , Irvine , USA

1995 - present


Professor, Department of Neurobiology and Behavior, University of California , Irvine , U.S.A.
Professor, Department of Physiology & Biophysics, University of California, Irvine, USA  

Membership of Societies
The Physiological Society
Society for Neuroscience
American Physiological Society
Biophysical Society

Editorial Boards

Journal of General Physiology
Biophysical Journal

2001. Excellence in Teaching. School of Biological Sciences, U.C. Irvine.

Recent Invited Presentations
Feb. 1993 Department of Molecular and Cellular Biology, University of California Davis .
April 1993 Southern California Confocal Microscopy Users Group
April 1993 Department of Physiology, University of California Los Angeles.
May 1993 XIth Annual Membrane Transport Workshop, "Ca 2+ transport and homeostasis". University of Montreal, Canada.
Feb. 1994 Department of Pharmacology, University of California Irvine.
April 1994 Ciba Foundation Symposium #188 "Calcium Waves, Gradients and Oscillations". London , England
April 1994 Welcome Centre for Medical Science open meeting on "Spatiotemporal Aspects of Calcium Signalling".
London, England.
July 1994 Department of Physiology and Biophysics, University of Tennessee , Memphis.
Sept. 1994 Channels-Receptors-Transporters Group. University of California Irvine.
Dec. 1994 Workshop on Calcium Oscillations and Waves. Marconi Center , Bodega Bay, California.
April 1995 Experimental Biology '95 Symposium on "Spatial and Temporal Aspects of Cellular Calcium Signaling". Atlanta, Georgia.
April 1995 Department of Physiology, University of Maryland at Baltimore.
May 1995 EMBO Practical Course "Use of Xenopus oocytes to study membrane transport and signal transduction". Tel Aviv University, Israel.
May 1995 IVth European Oocyte Club Meeting, Tel Aviv University, Israel.
June 1995 Gordon Conference on Calcium Signaling. New England College , New Hampshire.
Sept. 1995 Society of General Physiology Annual Meeting on "Organellar Ion Channels and Transporters". Woods Hole, Massachusetts.
Nov. 1995 Department of Physiology, University of Rochester School of Medicine, Rochester, NY.
Sept. 1996 21st European Symposium on Hormones and Cell Regulation, Mt. St . Odille, Alsace, France.
March 1997 Symposium on “Local Ca 2+ signalling in muscle and nerve” Annual meeting of Biophysical Society. New Orleans, LA.
April 1997 Workshop on “Mechanism of the Fertilization Ca 2+ wave” Lake Tahoe, CA.

July 1997
Meeting on “Biological Applications of New Microscopies”. British Biophysical Society, London , U.K. July 1997 “Calcium dynamics and cell signalling” International Society for Neurochemistry/American Society for Neurochemistry. Boston, MA.
Sept. 1997 “Invited guest” 22 nd European Symposium on Hormones and Cell Regulation. Mt. St. Odille, Alsace, France.
Dec. 1997 Department of Physiology, U. Texas Southwestern Medical Center. Dallas, Texas.
Feb. 1998 Workshop on “Calcium Dynamics in Cells”. Institute for Mathematics and its Applications. Univ. Minnesota , Minneapolis, MN.
July 1998 UCI Brain Imaging Workshop, Irvine, CA .
Sept. 1998 Department of Physiology, University of Durham, U.K.
Sept. 1998

Department of Pharmacology, Cambridge University, UK .

Sept. 1998 Society of General Physiology Annual Meeting on “Mechanisms and Functions of Local Calcium Signaling”. Woods Hole, Massachusetts.
May 1999 Society for Industrial and Applied Mathematics. Fifth Conference on Dynamical Systems. Snowbird, Utah.
Aug. 1999 Gordon Conference on Calcium Signaling. New Hampshire.
Oct. 1999 Department of Neuroscience, Tokyo University, Japan.
Oct. 1999 Eleventh International Symposium on Calcium-binding Proteins and Calcium Function in Health and Disease. Kisarazu, Japan.
Mar. 2000 Co-organizer and speaker. Workshop on “Nonlinear Dynamics of Calcium in Living Organisms”. Los Alamos National Laboratory, New Mexico.
June 2000 Department of Physiology, University of Massachusetts Medical School, Worcester, MA.
June 2000 Gordon Conference on Muscle: Excitation-Contraction Coupling. New Hampshire.
July 2000 Division de Physiologia, Universidad de Alicante, Spain.
July 2000 Instituto de Neurociencias, Universidad Miguel Hernandez, Spain .
Sept. 2000 “Synaptic transmission 100 years after Luigi Luciani.” Rome, Italy.
Oct. 2000 Workshop on Experimental and Theoretical Calcium Dynamics. Max-Plank Institute for Physics of Complex Systems, Dresden, Germany.
May 2001 Biophotonics Cluster Program, University of Wisconsin, Madison, WI .
June 2001 Physiological and Pathological Mechanisms of Calcium Signaling. AAAS meeting, UC Irvine.
June 2001 School of Biological Sciences, University of East Anglia , U.K.
Oct. 2001

Department of Neurobiology and Behavior, UC Irvine.

March 2002 Annual meeting of the American Physical Society, Indianapolis.
April 2002

Symposium on “Molecular bases for local Ca 2+ signals.” FASEB Meeting, New Orleans .

Aug. 2002 Workshop on “Wave Dynamics in Biological Excitable Media”. Aspen Center for Physics, Colorado.
March 2003 Symposium on “Stochastic Effects in Soft Condensed Matter Physics” American Physical Society meeting, Austin, Texas.
May 2003 Optical Biology Interest Group, UCI.
June 2003 Department of Immunology, University of Glasgow, UK .
Aug. 2003 Organizer and speaker, session on ‘Emerging Trends in Fluorescence Microscopy’. 2 nd International Symposium on Biophotonics, San Antonio , TX .
Sept. 2003 Joint organizer and speaker, Workshop on “Cellular Calcium Dynamics”, Kavli Institute for Theoretical Physics, UCSB.
Sept. 2003 Workshop on “Calcium Release and Cellular Calcium Signaling Domains”. Marbella, Chile .
Dec. 2003 Institute for Brain Aging and Dementia, UC Irvine.
Jan. 2004

Neuroscience Graduate Student Association, UC Riverside.

Jan. 2004 Workshop on “Signal Transduction: The Many Roles of Calcium”. Mathematical Biosciences Institute, Ohio State Univ.
Feb. 2004 Annual Meeting, Biophysical Society: Fluorescence Subgroup. Baltimore MD.
May 2004 Center for Theoretical Biological Physics, UCSD.
Aug. 2004

Special interest plenary lecture; ‘Imaging with Photons’. European Microscopy Congress, Antwerp, Belgium .

Sept. 2004 Session on “New Technologies for Tracking Cells in vivo”, 20 th International Congress of the Transplantation Society. Vienna, Austria .
Sept. 2004 Department of Pharmacology, University of Cambridge, U.K.
Sept. 2004 EMBO Workshop on “Calcium Signaling and Disease”. Capri, Italy
March 2005 3 rd International Conference on Computational Cell Biology, Lenox , MA .
June 2005 Gordon Conference on Calcium Signaling, Oxford, UK .
Sept. 2005
March 2006
Aug. 2006
Sept. 2006

HHMI meeting on in vivo imaging. Washington, DC .
Rosalind Franklin School of Medicine, Chicago.
8th Giambigini Winter Conference, University of Buenos Aires, Argentina.
Gordon Conference on Bioelectrochemistry, Aussois, France.

Current Research Support
‘Elementary Events of Calcium Signaling’ . NIH GM-48071. PI – I. Parker. 2003-2007.
This project aims to elucidate the mechanistic basis underlying the generation and functions of local and global Ca 2+ signals.

‘Multi-scale observation and modeling of IP 3/Ca signaling” . NIH Consortium Award. PI – J. Pearson ( Los Alamos ); PI ( Irvine component) I. Parker. 2002-2007.
This project utilizes multi-scale mathematical simulation to develop a comprehensive model of intracellular IP 3-mediated Ca 2+ signaling. My role is to provide experimental data and biological input on elementary Ca 2+ events and waves, and to work in collaboration with mathematicians and physicists to develop mathematical models of these processes.

‘Presenilin Function and Calcium Regulation in Alzheimer’s Disease’ NIH. ZAG1 PKN-7. 2000-2005. Alzheimer’s Disease Research Center of UCI. PI – C. Cotman; Project Leader – F. LaFerla; Co-PI – I. Parker.
This project examines the involvement of disruptions of Ca 2+ homeostasis in Alzheimer’s disease, by using molecular biological, pharmacological and imaging techniques to study the effects of presenilin mutations in Xenopus oocytes and cultured neurons. My role is to direct high-resolution imaging experiments and to provide expertise in Ca 2+ signaling.

‘The role of calcium ions in lymphocyte activation’ PI – M.D. Cahalan; Co-investigator – I. Parker. NIH. 2002-2007.
This project utilizes live cell imaging techniques to explore the roles of cell motility, Ca 2+ signaling and ion channel function in the initiation of the immune response by T lymphocytes. My role on this project is to develop and direct a multi-photon imaging system for studying T cell behavior within intact lymphoid tissue, and to collaborate on analysis and interpretation of these data.

1146 Mc Gaugh Hall
University of California, Irvine
Irvine, CA 92697-4550
Lab Tel: 949-824-7833
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last updated 02/2005. Please send enquiries to ianparkerlabweb@gmail.com